منابع مشابه
Sex Determination: Controlling the Master
Sex is determined in Drosophila by the activity of the Sex-lethal master regulator. Activity of Sex-lethal is initiated early in females by chromosome-counting transcription factors, then reinforced by signaling through the Janus kinase pathway.
متن کاملAsymmetric spermatocyte division as a mechanism for controlling sex ratios.
Although Mendel's first law predicts that crosses between XY (or XO) males and XX females should yield equal numbers of males and females, individuals in a wide variety of metazoans transmit their sex chromosomes unequally and produce broods with highly skewed sex ratios. Here, we report two modifications to the cellular programme of spermatogenesis, which, in combination, help to explain why m...
متن کاملPreventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age, and sex.
BACKGROUND Hypertension is related to significant morbidity and mortality rates from coronary heart disease (CHD). This report examines the relative and absolute impact on risk for CHD by controlling hypertension to high normal and optimal levels. METHODS Among all subjects with untreated or inadequately treated hypertension in the National Health and Nutrition Examination Survey (NHANES) III...
متن کاملPlasticity of gene-regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators.
Sexual dimorphism is one of the most pervasive and diverse features of animal morphology, physiology, and behavior. Despite the generality of the phenomenon itself, the mechanisms controlling how sex is determined differ considerably among various organismic groups, have evolved repeatedly and independently, and the underlying molecular pathways can change quickly during evolution. Even within ...
متن کاملcontrolling
controlling is a very important function of every manager. controlling is based and closely related to planning or the first function of management. these two functions are so related to each other that may be viewed as the blades of a pair of scissors. the scissors can not work unless there are two blades. without plans, control is not possible. theoretically, the concept of concept of control...
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ژورنال
عنوان ژورنال: Science
سال: 2011
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.333.6039.137-b